A Brentwood father pleaded not guilty Wednesday to an indictment charging him with second-degree murder and manslaughter in the death of his seven-week-old daughter.

Angelo Deleon, 51, appeared in State Supreme Court in Riverhead, where a judge set bail at $250,000 cash or bond.

Suffolk County prosecutors alleged that the infant, Genesis Deleon, was shaken to death by her father on Oct. 30 at their Brentwood home. He was her lone caretaker that day, prosecutors said.

Deleon was also charged with reckless assault of a child for a separate incident that allegedly occurred several days before the girl’s death. He pleaded not guilty to that charge as well.

Deleon’s next court date is Dec. 17.

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